DiVenn is an interactive and integrated web-based tool for comparing gene lists. The current version is
“2.0”.
Introduction
Gene expression data generated from multiple biological states (mutant sample, double mutant sample and wild-type samples) are often compared via Venn diagram tools. It is of great interest to know the expression pattern between overlapping genes and their associated gene pathways or gene ontology terms. We developed DiVenn – a novel web-based tool that compares gene lists from multiple RNA-Seq experiments in a force directed graph, which shows the gene regulation levels for each gene and integrated KEGG pathway and gene ontology (GO) knowledge for the data visualization. Divenn2 includes exciting new features:
Expanded the number of species that can now be supported for gene analysis (now 28 species in total), including lesser-model species
Support for a new ID type: Ensembl IDs. NCBI/Entrez, Uniprot, and Ensembl IDs are now supported depending on the target organism
Increased number of experiments allowed for visualization to 10 total experiments
More color and shape options for visualizations
Font size options
Pathway details and KEGG pathway enrichment details tables
Gene ontology details and GO enrichment details tables
Right-click options for each gene group to generate gene group details tables
Single gene detail tables
An updated database to include new species and provide mapping to other ID types if necessary/available
Generation of tables and bar chart visualizations for GO enrichment and KEGG enrichment analysis
Three Key Features
Informative force-directed graph with gene expression levels to compare multiple data sets;
Interactive visualization with biological annotations and integrated pathway and GO databases, which can
be used to subset or
highlight gene nodes to pathway or GO terms of interest in the graph;
High resolution image and gene-associated information export.
Tutorial
Click below to
watch a tutorial video, or
view Source Files for more information.